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Traditional Medicine and Ph...
What is Topical Lidocaine?
Lidocaine (also known as xylocaine, lignocaine) is a local anesthetic. It is applied either as a cream or a patch to provide a sustained effect. The duration of effect can be as little as one hour or as long as several hours, depending on the mechanism of application.
It has been found useful in the management of postherpetic neuralgia and other regional neuropathic pain problems. The most common applications of topical lidocaine are gel or skin patches.
How does it work?
Lidocaine alters nerve signals by blocking sodium channels and inhibiting the communication of pain. Not only does it halt the pain signals from transmitting, it can stop them from beginning as well.
Derry S, Wiffen PJ, Moore RA, Quinlan J.
Topical lidocaine for neuropathic pain in adults.
Cochrane Database Syst Rev. 2014 Jul
An overview of singles and associated clinical trials, genetics, journal articles and patient han...
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The most relevant research and evidence on neuropathic pain
A prospective randomized study to analyze the efficacy of balanced pre-emptive analgesia in spine surgery.
Spine J. 2018 Oct 22. pii: S1529-9430(18)31167-7. doi: 10.1016/j.spinee.2018.10.010.
Brain and spinal stimulation therapies for phantom limb pain: a systematic review.
Health Technol Assess. 2018 Nov;22(62):1-94. doi: 10.3310/hta22620.
Pregabalin to improve postoperative recovery in bariatric surgery: a parallel, randomized, double-blinded, placebo-controlled study.
J Pain Res. 2018 Oct 17;11:2407-2415. doi: 10.2147/JPR.S176468. eCollection 2018.
Clinical effect and safety of pulsed radiofrequency treatment for pudendal neuralgia: a prospective, randomized controlled clinical trial.
J Pain Res. 2018 Oct 16;11:2367-2374. eCollection 2018.
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