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Traditional Medicine and Ph...
What is Topical Lidocaine?
Lidocaine (also known as xylocaine, lignocaine) is a local anesthetic. It is applied either as a cream or a patch to provide a sustained effect. The duration of effect can be as little as one hour or as long as several hours, depending on the mechanism of application.
It has been found useful in the management of postherpetic neuralgia and other regional neuropathic pain problems. The most common applications of topical lidocaine are gel or skin patches.
How does it work?
Lidocaine alters nerve signals by blocking sodium channels and inhibiting the communication of pain. Not only does it halt the pain signals from transmitting, it can stop them from beginning as well.
Derry S, Wiffen PJ, Moore RA, Quinlan J.
Topical lidocaine for neuropathic pain in adults.
Cochrane Database Syst Rev. 2014 Jul
An overview of singles and associated clinical trials, genetics, journal articles and patient han...
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The most relevant research and evidence on neuropathic pain
Adverse events associated with medium- and long-term use of opioids for chronic non-cancer pain: an overview of Cochrane Reviews.
Cochrane Database Syst Rev. 2017 Oct 30;10:CD012509. doi: 10.1002/14651858.CD012509.pub2.
Traditional manual acupuncture combined with rehabilitation therapy for shoulder hand syndrome after stroke within the Chinese healthcare system: a systematic review and meta-analysis.
Clin Rehabil. 2017 Sep 1:269215517729528. doi: 10.1177/0269215517729528.
Selective Cannabinoids for Chronic Neuropathic Pain: A Systematic Review and Meta-analysis.
Anesth Analg. 2017 Nov;125(5):1638-1652. doi: 10.1213/ANE.0000000000002110.
Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Pain Physician. 2017 Sep;20(6):E755-E796.
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