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Traditional Medicine and Ph...
What is Topical Lidocaine?
Lidocaine (also known as xylocaine, lignocaine) is a local anesthetic. It is applied either as a cream or a patch to provide a sustained effect. The duration of effect can be as little as one hour or as long as several hours, depending on the mechanism of application.
It has been found useful in the management of postherpetic neuralgia and other regional neuropathic pain problems. The most common applications of topical lidocaine are gel or skin patches.
How does it work?
Lidocaine alters nerve signals by blocking sodium channels and inhibiting the communication of pain. Not only does it halt the pain signals from transmitting, it can stop them from beginning as well.
Derry S, Wiffen PJ, Moore RA, Quinlan J.
Topical lidocaine for neuropathic pain in adults.
Cochrane Database Syst Rev. 2014 Jul
An overview of singles and associated clinical trials, genetics, journal articles and patient han...
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The most relevant research and evidence on neuropathic pain
Efficacy of 8 Different Drug Treatments for Patients With Trigeminal Neuralgia: A Network Meta-analysis.
Clin J Pain. 2018 Jul;34(7):685-690. doi: 10.1097/AJP.0000000000000577.
Efficacy of opioids versus placebo in chronic pain: a systematic review and meta-analysis of enriched enrollment randomized withdrawal trials.
J Pain Res. 2018 May 3;11:923-934. doi: 10.2147/JPR.S160255. eCollection 2018.
Pectoral I Block Does Not Improve Postoperative Analgesia After Breast Cancer Surgery: A Randomized, Double-Blind, Dual-Centered Controlled Trial.
Reg Anesth Pain Med. 2018 Apr 18. doi: 10.1097/AAP.0000000000000779.
Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases.
J Pain Res. 2018 Apr 23;11:837-842. doi: 10.2147/JPR.S160556. eCollection 2018.
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