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Traditional Medicine and Ph...
What is Topical Lidocaine?
Lidocaine (also known as xylocaine, lignocaine) is a local anesthetic. It is applied either as a cream or a patch to provide a sustained effect. The duration of effect can be as little as one hour or as long as several hours, depending on the mechanism of application.
It has been found useful in the management of postherpetic neuralgia and other regional neuropathic pain problems. The most common applications of topical lidocaine are gel or skin patches.
How does it work?
Lidocaine alters nerve signals by blocking sodium channels and inhibiting the communication of pain. Not only does it halt the pain signals from transmitting, it can stop them from beginning as well.
Derry S, Wiffen PJ, Moore RA, Quinlan J.
Topical lidocaine for neuropathic pain in adults.
Cochrane Database Syst Rev. 2014 Jul
An overview of singles and associated clinical trials, genetics, journal articles and patient han...
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The most relevant research and evidence on neuropathic pain
Cannabinoids, cannabis, and cannabis-based medicine for pain management: a systematic review of randomised controlled trials.
Pain. 2020 May 18. doi: 10.1097/j.pain.0000000000001929.
A Systematic Literature Review of Dorsal Root Ganglion Neurostimulation for the Treatment of Pain.
Pain Med. 2020 Aug 1;21(8):1581-1589. doi: 10.1093/pm/pnaa005.
Postoperative Single-shot Epidural Fentanyl and Bupivacaine for Postoperative Analgesia After Lumbar Decompression: A Prospective, Double-blind Randomized Study.
Spine (Phila Pa 1976). 2020 Aug 1;45(15):1017-1023. doi: 10.1097/BRS.0000000000003449.
Methadone in Pain Management: A Systematic Review.
J Pain. 2020 Jun 26. pii: S1526-5900(20)30044-4. doi: 10.1016/j.jpain.2020.04.004.
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