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Traditional Medicine and Ph...
What is Topical Lidocaine?
Lidocaine (also known as xylocaine, lignocaine) is a local anesthetic. It is applied either as a cream or a patch to provide a sustained effect. The duration of effect can be as little as one hour or as long as several hours, depending on the mechanism of application.
It has been found useful in the management of postherpetic neuralgia and other regional neuropathic pain problems. The most common applications of topical lidocaine are gel or skin patches.
How does it work?
Lidocaine alters nerve signals by blocking sodium channels and inhibiting the communication of pain. Not only does it halt the pain signals from transmitting, it can stop them from beginning as well.
Derry S, Wiffen PJ, Moore RA, Quinlan J.
Topical lidocaine for neuropathic pain in adults.
Cochrane Database Syst Rev. 2014 Jul
An overview of singles and associated clinical trials, genetics, journal articles and patient han...
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The most relevant research and evidence on neuropathic pain
Randomized, double-blind, controlled trial of a combination of alpha-lipoic acid and pregabalin for neuropathic pain: the PAIN-CARE trial.
Pain. 2023 Sep 7. doi: 10.1097/j.pain.0000000000003038.
Psychological therapies delivered remotely for the management of chronic pain (excluding headache) in adults.
Cochrane Database Syst Rev. 2023 Aug 29;8(8):CD013863. doi: 10.1002/14651858.CD013863.pub2.
Rehabilitation Interventions for Complex Regional Pain Syndrome: An Overview of Systematic Reviews.
Clin J Pain. 2023 Sep 1;39(9):473-483. doi: 10.1097/AJP.0000000000001133.
A Network Meta-Analysis of Randomized Clinical Trials to Assess the Efficacy and Safety of Antiviral Agents for Immunocompetent Patients with Herpes Zoster-Associated Pain.
Pain Physician. 2023 Jul;26(4):337-346.
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